Question | Answer |
---|---|
1st Generation Antipsychotics | Chlorpromazine, Thioridazine Perphenazine Haloperidol, Fluphenazine |
Atypical antipsychotics | Clozaril (clozapine), Risperidal (risperidone), Seroquel (quetiapine), Zyprexa (olanzapine) |
Mood Stabilizers | Lithium (eskalith) |
Antieplectics | Tegretol (carbamzepine), Depakote (valproic acid), Lamictal (lamotrigine), Klonopin (clonazepam) |
Tricyclic Antidepressants | Chlomipramine, Amitriptyline, Imipramine, Nortryptiline, Despiramine |
SSRIs | Prozac (fluoxetine), Paxil (paroxetine), Celexa (citalopram), Zoloft (sertraline), Luvox (fluvoxamine), Lexapro (escitalopram) |
MAOIs | Phenelzine (sedating), Tranylcipramine (stimulating) |
Atypical/Novel Antidepressants | Desyel (trazadone), Wellbutrin (bupropion), Effexor (venalfaxine), Remeron (mirtazapine), Cymbalta (duloxetine) |
Antianxiety/Anxiolytics | Benzodiazepines - Diazepam, Alprazolam, Clonazepam, Lorazepam |
Antidote for Antianxiety OD | Flumazinil |
Blocks Dopamine in Basal Ganglia | Typical antipsychotics - Chlorpromazine, Thioridazine (low) Perphenazine (mid) Haloperidol, Fluphenazine (high) |
Common side effects of Typical antipsychotics | EPS, anticholinergic effects, sedation, weight gain high - worse side effects |
Antipsychotic that causes agranulocytosis | Clozapine |
Quetapine side effects/uses | weight gain, sedation; useful in mania, sleep |
Olanzapine side effects | weight gain |
Lithium toxicity - early signs | ATAXIA, n/v/d, thirst, polyuria, slurred speech, muscle weakness |
Expected side effects of Lithium | lethargy, weight gain, fine hand tremors, blurred vision |
Antiepileptics are used for what? | used to help stabilize mood disorders |
carbamazepine & oxcarbazepine monitor for | CBC - AGRANULOCYTOSIS |
Valproate monitor for | CBC, LFT, pregnancy, PCOS |
Side effects of TCA's | anticholinergic sie effects (blurred vision, urinary retention, dry moth, constipation) sedation, orthostatic hypotension, sexual dysfunction |
Do not take MAOI's with? | TCAs (2 weeks between these meds) and SSRIs |
SSRIs and St. Johns Wort taken together can cause what? | Serotonin Reaction Syndrome |
Serotonin Reaction Syndrome s/s | abdominal pain, diarrhea, fever (100 - 103), diaphoresis, tachycardia, increased BP, delirium, myoclonus, irritability, hostility, mood changes |
What class of drugs if 1st line treatment for depression? | SSRIs |
SSRI benefits | no anticholinergic side effects, faster onset than TCAs |
MAOI client teaching | no foods containing tyramine, no OTC cold meds, no antihypertensive meds (lots of drug-drug) interactions |
Tyramine foods | aged cheese and meats, pickled foods, sausage, beer, wine, chocolate, over-ripr fruits, bananas, avocados, soy sauce, dried fruits, caffiene |
Some cheeses that are ok with MAOIs | cottage cheese and cream cheese |
Side effects of MAOIs | Orthostatic hypotension, weight gain, edema, cardiac rate/rhythm, sex dysfunction, sedation, weakness/fatigue, muscle cramps |
3rd line treatment of depression | MAOIs |
Alternative treatment for depression | Electro-convulsive therapy - 2-3 x's a week for 6-12 treatments |
trazadone, nefazodone helps with | sleep; side effect: priapism |
Bupropion has low incidence of this side effect compared to other antidepresants? | sexual dysfunction side effects |
Benzodiazepines are contraindicated with what drugs? | CNS depressants, ETOH, opiates - can cause life threatening respiratory depression |
Benzodiazepines are contraindicated for what clients? | Pregnant, nursing women, those with substance abuse history, use in the elderly can cause falls and broken bones |
BuSpar (buspirone) | anti-anxiety: GAD, MDD |